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In vitro, astrocytes derived from induced pluripotent stem cells obtained from patients with FTD-MAPT showed hypertrophy, elevated GFAP protein levels, disease-associated changes in TAU expression, increased vulnerability to oxidative stress, and protein ubiquitination 231

Treasure Island, FL: StatPearls Publishing.Google Scholar 12 , Pantothenic Acid, Biotin, and Choline

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& Sablani, S

DHA induces cell death through the production of ROS and the upregulation of CHOP in fibroblast-like synovial cells from human rheumatoid arthritis patients